One of my favorites.
The Witchblade is a powerful weapon that transforms its possessor. It is only passed to women, and it is unknown who will be chosen.
(Inspired by the American comic-book with the same name)
http://www.youtube.com/watch?v=i0VSdan89coI think the anime takes place 200 years after the American Comic.
There is also a manga "Witchblade: Takeru" & a novel "Witchblade Lost Generation: Midori no Shōjo."
The timeline goes Manga, then Novel, then anime.
-wiki
http://www.animenewsnetwork.com/video/8708/