My home con just concluded it's virtual con.
Compared to the Kuroneko con. I liked it better.
Radcon did it through Discord and I felt like it was a good platform. You can allow for microphone, but you have less distraction from people muttering (like you would at a normal con). With each "panel room" you had a chat which allowed for questions and commentary.
You also can do streaming, both games and shows.
My friend and I had a blast watching Avatar and RWBY last night with a group of other people.
Kuroneko con did panels through Youtube and I feel that didn't allow for as much interaction.